Metabolic regulation of calcium and phosphorus - GSP
Major function of vitamin D is to regulate the level of calcium and phosphorus in blood into normal scope and to keep balance. Concentration of calcium and phosphorus in blood is regulated within the range that can help the function of neural muscle or bone minerals. This regulation increases the absorption of calcium and phosphorus in small intestine by 1,25(OH)2D.If intake of vitamin D is insufficient, there is any disturbing factor in absorbing fat, its generation in winter seasons is insufficient, the level of 25(OH)D3 becomes lower and the level of 1,25(OH)2D3 and calcium in blood lower too. At that moment, the concentration of parathyroid glans hormone is increased and its increase increases flow-out of minerals in bone which leads to loss of bone minerals. Therefore, the main action of 1,25(OH)2D acts for small intestine and bones to make the absorption of calcium and phosphorus in meal efficient. It regulates blood serum calcium level to proper range for cell activat